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Multiple sclerosis treatment considered for Rett Syndrome
Glatiramer acetate (also known as Copolymer 1, Cop-1, or Copaxone – as marketed by Teva Pharmaceuticals) is an immunomodulator drug currently used to treat multiple sclerosis and is hypothesized to have some possible affect on patients with Rett Syndrome. It was published on October 14th on PubMed by Ben-Zeev B, Aharoni R, Nissenkorn A, Arnon R. that by raising the Brain derived neurotrophic... -
Mercury exposure, nutritional deficiencies and metabolic disruptions may affect learning in children.
Behav Brain Funct. 2009 Oct 27;5:44. Mercury exposure, nutritional deficiencies and metabolic disruptions may affect learning in children. Dufault R, Schnoll R, Lukiw WJ, Leblanc B, Cornett C, Patrick L, Wallinga D, Gilbert SG, Crider R. United Tribes Technical College, Bismarck, ND, USA. rdufault@uttc.edu. ABSTRACT: Among dietary factors, learning and behavior are influenced not only by nutrients... -
The possibility and probability of a gut-to-brain connection in autism.
Ann Clin Psychiatry. 2009 Oct-Dec;21(4):205-11. The possibility and probability of a gut-to-brain connection in autism. Reichelt KL, Knivsberg AM. Department of Pediatric Research, Rikshospitalet Medical Centre, University of Oslo, Oslo, Norway. karlr@ulrik.uio.no BACKGROUND: We have shown that urine peptide increase is found in autism, and that some of these peptides have a dietary origin. To be ... -
Immune activation of peripheral blood and mucosal CD3+ lymphocyte cytokine profiles in children with autism and gastrointestinal symptoms.
Gastrointestinal pathology, characterized by lymphoid nodular hyperplasia and entero-colitis, has been demonstrated in a cohort of children with autistic spectrum disorder (ASD). Systemic and intestinal mucosal immune dysregulation was assessed in ASD children with gastrointestinal (GI) symptoms (n = 18), and typically developing controls (n = 27), including non-inflamed controls (NIC) and inflame... -
Intestinal lymphocyte populations in children with regressive autism: evidence for extensive mucosal immunopathology.
Inflammatory intestinal pathology has been reported in children with regressive autism (affected children). Detailed analysis of intestinal biopsies in these children indicates a novel lymphocytic enterocolitis with autoimmune features; however, links with cognitive function remain unclear. To characterize further, the nature and extent of this disease we examined the mucosal infiltrate using flow... -
Probiotics and prevention of atopic disease: 4-year follow-up of a randomised placebo-controlled trial.
Perinatal administration of the probiotic Lactobacillus rhamnosus strain GG (ATCC 53103), reduces incidence of atopic eczema in at-risk children during the first 2 years of life (infancy). We have therefore assessed persistence of the potential to prevent atopic eczema at 4 years. Atopic disease was diagnosed on the basis of a questionnaire and a clinical examination. 14 of 53 children receiving l...

