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  • Lyme disease and Autism connection hypothesis

    The association between tick-borne infections, Lyme borreliosis and autism spectrum disorders.
    Bransfield RC, Wulfman JS, Harvey WT, Usman AI.

    Department of Psychiatry, Riverview Medical Center, 225 State Route 35, Red Bank, NJ, United States. bransfield@comcast.net

    Chronic infectious diseases, including tick-borne infections such as Borrelia burgdorferi may have direct effects, promote other infections and create a weakened, sensitized and immunologically vulnerable state during fetal development and infancy leading to increased vulnerability for developing autism spectrum disorders. A dysfunctional synergism with other predisposing and contributing factors may contribute to autism spectrum disorders by provoking innate and adaptive immune reactions to cause and perpetuate effects in susceptible individuals that result in inflammation, molecular mimicry, kynurenine pathway changes, increased quinolinic acid and decreased serotonin, oxidative stress, mitochondrial dysfunction and excitotoxicity that impair the development of the amygdala and other neural structures and neural networks resulting in a partial Klüver-Bucy Syndrome and other deficits resulting in autism spectrum disorders and/or exacerbating autism spectrum disorders from other causes throughout life. Support for this hypothesis includes multiple cases of mothers with Lyme disease and children with autism spectrum disorders; fetal neurological abnormalities associated with tick-borne diseases; similarities between tick-borne diseases and autism spectrum disorder regarding symptoms, pathophysiology, immune reactivity, temporal lobe pathology, and brain imaging data; positive reactivity in several studies with autistic spectrum disorder patients for Borrelia burgdorferi (22%, 26% and 20-30%) and 58% for mycoplasma; similar geographic distribution and improvement in autistic symptoms from antibiotic treatment. It is imperative to research these and all possible causes of autism spectrum disorders in order to prevent every preventable case and treat every treatable case until this disease has been eliminated from humanity.

    PMID: 17980971 [PubMed - indexed for MEDLINE]

    Source: http://www.ncbi.nlm.nih.gov/pubmed/17980971?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

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    Lyme disease and Autism connection hypothesis5.053

16 Comments

  1. I am personally interested in knowing if there is a true connection between lyme disease and some autism diagnosis. My own autistic daughter displays signs of Lyme disease yet was never showed an obvious bite mark.

    The hypothesis of second generation Lyme infection is really interesting. This will be something I will have my own daughter tested for and be posting updates here as well.

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    • #2 ChronicLymie says:
      June 28th, 2017 at 12:32 pm

      Hi Jeramie,

      You must get your child tested using the Western Blot test or better, (DNA test). I grew up covered in Jersey ticks and never once in my life had the “rash” only 50% of the people get the rash, no matter what you read on the internet. It doesn’t matter what state you live in. Please know the longer your child has lyme bacteria in their system, the less likely the ELISA test will work. Which is the only test a family doc or “specialist” will use.

      You can get a referral from www [dot] lymediseaseassociation [dot] org

      Lyme bacteria is metal sensitive… which is the mercury to autism link.

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    • #3 Will Wiegman says:
      June 28th, 2017 at 10:12 pm

      Nope, Autism related to the 2nd year big vaccine shot is now undeniably linked to a Chronic Congenital Lyme Induced Severe Thiocyanate Defciciency.
      A 90 day, double blind study of hundreds of Congenital Lyme and Autistic kids all over the world is only in it’s 17th day and dozens of kids are waking up between day 14-16, talking again, playing sports, and singing songs! Their parents, coaches, teachers and personal Doctors monitoring them are astounded as am I.
      The trial was to see if the Wiegman Pulsed Lyme Ptotocol can cure Congenital Lyme, which it did with the first couple of test subects, which led to the bigger group being formed.
      Not only does the Wiegman Pulsed Lyme Protocol cure congenital lyme, only the dietary preparations before the antibiotics even start is curing the Autism in the test subjects!
      Only Non-GM and Non-GMO food sources of the Thiocyanate precursor, HMDB35030, are being used to reverse the Thiocyanate Deficiency.

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  2. #4 ChronicLymie says:
    June 28th, 2017 at 2:20 pm

    Why was my comment deleted?

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    • It wasn’t deleted, it just was not approved right away. First time comments have to be approved to reduce spam. Now that you have one approved with your current email, you won’t have to wait for approval.

      Thanks for the comment and information about Lyme above. I really appreciate the information as I arm myself with what I should know on our November 13, 2009 appointment for our daughter.

      I take it you had Lyme? Did or do you also have an autistic child that tested positive as well?

      Thanks,

      Jeramie

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  3. #6 ChronicLymie says:
    June 28th, 2017 at 3:56 pm

    Duh… moderation. Geeze Lyme Brain going :-)

    No I have no children yet. My Lyme doc treats autism though. Yes I have lyme… negative on the ELISA test, but positive on the Western Blot. They will tell you that the ELISA test has the Western Blot confirmation, but it only goes out for confirmation if the ELISA test is positive. The ELISA test only checks for the antibodies, so if someone has had lyme for 6 months or more the body stops producing antibodies. If your doctors insist on the ELISA test, it’s worth a try, but a negative result on the ELISA test does not mean negative for lyme.

    Doctors are afraid of treating for lyme disease because they are afraid of losing their license for treating with long term antibiotics. There is a really good documentary about lyme. Search you tube for “Under our Skin”. Watch the other Lyme videos there as well. Do not go to the ALDF website… that is a pharmaceutical front.

    Looking back my mother may have had lyme while she was pregnant with me. I had massive chronic ear and nose infections as a baby, and had my adenoids taken out when I was five. I was Celiac then but have grown out of it. I do still have a casein allergy, (dairy) that is common amongst autistic patients. Then when I felt better I entered the gifted program at school. But in the 70′s we didn’t get half as much mercury filled vaccines like the kids get now a days.

    Lyme bacteria can be sexually tranmitted, and is transmitted through many biting insects not just ticks, (mosquitoes).

    Lyme symptoms that relate to an autistic diagnosis are: Poor Eye Contact, uncontrollable movements (rocking, arm flailing,) dairy allergies, IBS / leaky gut, social problems, not understanding what is meant by what is being said, tantrums, trouble speaking/ no speaking, singing – songs in head, humming instead of speaking in words, repetive behaivors, OCD, list goes on and on. Lyme Patients have been trying to get the word out for years on this.

    This part is pure opinion but… I believe it is no coincidence that NJ has the highest rate of Autism. The tri-state area is endemic for lyme.

    Good luck with your appointment! Please demand the Western Blot or better, or find another doctor.

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    • Thanks again. Very helpful. Ear infections, gluten allergies, casein allergies, and several more symptoms is what my daughter has. You can read my article here about how I believe that my daughter became autistic, featured on the homepage, if you wish.

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  4. #8 ChronicLymie says:
    June 28th, 2017 at 4:14 pm

    I’m on your facebook site now… Sounds like the story of my life… luckily my metal levels weren’t that high.

    One more thing… as a toddler I would sit in the corner of the room facing away from everybody.

    Sugar helps lyme bacteria reproduce. Lyme loves a high sugar diet. Lyme Bacteria is light sensitive, noise sensitive, chemical sensitive, metal sensitive, and food sensitive.

    There is also a simple blood test to see all of the food allergies.

    I am just so happy that someone is willing to get the test done. I’ll follow your progress on Facebook! :-)

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  5. my son has and I just returned from the natropath where he was recently placed on gf/cf diet. Thru nutiotional microscopy the natropath referred me to a lyme specialist for my son. He has typical autistic symptoms and little language.

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  6. We live in virginia, and my son has some sign of autism,but i think he has lyme , if i can get a docor information will be great, i took him to a phd holdert in biochimistrey, but it was a ripoff, she charged us more then 2000$ in 3 visits.
    rasha

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  7. Very informative article post.Really looking forward to read more. Really Great.

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  8. My 4 year old son who has Autism, was just tested for Lyme and he is positive. I was then tested and I am positive also. His twin sister is being tested, and I’m pretty sure she will be positive – I am assuming I gave it to them. I think all kids with Autism should be tested even if you don’t live in an endemic area – we are in the Detroit Metro area of Michigan.

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  9. I treated my 2 year old for lyme induced autism-after his vaccine he was autistic overnight, the vaccines weakened his immune system and a dormant (hidden) lyme infection took over. As the lyme was treated the autism lifted. He is now 5 and is doing well !

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    • kim I am so happy to here that he is doing well my daughter to has just recently tested positive for lyme she is 3 1/2 years old she also had an adverse reaction to vaccine shots and at 2years of age she was diagnosed with autism, weve done biomed which has helped her a lot.. But would you mind sharing what it is you did to treat his lyme to lift his autism ..

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  10. My daughter just tested positive for Lyme. My 5 yr old granddaughter, diagnosed on the spectrum age 2,
    and her 3year old brother are going to be tested.

    My granddaughter’s primary symptoms now after 2.5 years of intensive bio-medical txment, are digestive
    track and language delay, both of which are significantly improved.
    My question: is there a proven treatment for toddlers
    on the spectrum for lyme disease? And what is it?

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  11. #16 Jon Garman says:
    June 28th, 2017 at 9:18 pm

    In response to ChronicLymie… I have two sons, 8 & 12. The 8 year old is autistic and was diagnosed as moderate to severe by specialists at the age of 3, of course, after being self-diagnosed by me, his father. He was unvaccinated. My 12 year old was, however, and with the exception of being anaphylactic to dairy at birth, was quite normal. Living in Florida from 2002 to 2007, we went on vacation and put our dog in a kennel for 3 weeks. A clean, undiseased dog, he came back to us looking normal, but thinner in weight. About a week or so later, we noticed what looked like rice grains in our bed. I thought my wife had been eating in bed, but was wrong. He had contracted worms from the vet hotel. My dog slept with us, so naturally I came to the conclusion and successful diagnosis of my dog having worms. Examining my dog further, I noticed he was covered with nymph tics, the ones associated with being a Lyme carrier. I didn’t know a single thing about lymes disease at the time, but knew I had to get rid of the tics. I had no idea what was causing my episodes of heartburn and heart palpitations. My eldest son was 2 at that time, and my autistic child wouldn’t be born for another 2 years. Fast forward to 2008… My autistic son was 1, and seemed very normal until he caught some kind of rash that looked like chicken pox. He regressed into autism slowly from that moment on. Approximately one year later, I had what was either a bout of pancreatitis or hepatitis followed by an allergic reaction to all things dairy. Approximately two years later, my entire family of four came down with a rash that looked like the same rash my autistic son had when he was one. Coincidentally, my wife suddenly had a reaction to all things dairy. What’s interesting, is that my wife and I had multiple symptoms associated with autism, while my autistic boy – who was already on the fast track to recovery because of our biomedical intervention protocol – seemed unchanged. Our eldest son, on the other hand, coincidentally developed a tic (Involuntary muscle movement). He then started toe walking, as well as having other symptoms associated with autism. Tics are a part of Tourette’s syndrome, which is an autism spectrum disorder. So all four of us were experiencing multiple symptoms associated with autism. After my 8 year old was professionally diagnosed at 3, I vowed to get to the bottom of what caused my unvaccinated son’s autism. I started doing research, and have been for the last 5 years. After my eldest son had developed his tic, all four of us started taking Hyperbaric Oxygen Therapy (The children were the only ones actually receiving oxygen). After a week of treatment, my eldest son’s tics were worsening. We went back to the neurologist that approved our treatments. The first words out of her mouth were “Lymes… Have him tested for Lymes disease.” The first thing I did when I got home was to start researching Lymes disease. Then we got tested. Of course, the ELISA tests were negative. I have been spending the last few years getting nowhere with the western medical doctors in getting Lymes diagnosis. I was, however, able to get a 30 day of doxycycline from my doctor, which helped relieve some symptoms but did not eradicate the Lymes and surely the co-infections that go along with it. Just recently, my dog died. I took the opportunity to send my dog to a school where they do necropsies on animals. I told the doctor what to look for, as my suspicions were that my dog actually did have Lymes disease and had given it to us. Final results are at the moment pending a PCR test. On the phone, however, the professor performing the necropsy told me that his findings were consistent with Lymes, and that until the PCR came back, he was 80% positive that my dog did in fact have Lymes. Just before reading your post, I had been talking with my wife about how I was seeing so many blogs from people from New Jersey saying that they had Lymes. I had also told her that, coincidentally, New Jersey has the highest rates of autism in the U.S. Like I said before, I have been researching autism extensively over the last 5 years. I found that there is one place that has the lowest autism rates on earth, rates that correlate with the genetic autism rates, rates that held steady through the 40′s, 50′s and 60′s… That is, until around 1977, when the rates of autism started to escalate. That place? The isolated island of Cuba. Lymes is found on every continent except for Antartica. Cuba just happens (Coincidentally) to have zero cases of Lymes. What’s even more interesting? There is no such thing as a coincidence… Things happen through a scientific principle called “Cause and effect.” Just thought you might find this interesting.

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